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Translocation of TRPV4-PI3Kγ complexes to the plasma membrane drives myofibroblast transdifferentiation
Myofibroblasts are key contributors to pathological fibrotic conditions of several major organs. Fibroblast transdifferentiation into myofibroblasts requires both a mechanical signal and transforming growth factor beta (TGF-β) signaling. The cation channel transient receptor potential vanilloid 4 (T...
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| Опубликовано в: : | Sci Signal |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7001959/ https://ncbi.nlm.nih.gov/pubmed/31719171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aau1533 |
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