Multiplex Chromatin Interactions with Single Molecule Precision

Genomes of higher organisms are extensively folded into three-dimensional (3D) chromosome territories within the nucleus(1). Advanced 3D genome mapping methods that combine proximity ligation and high-throughput sequencing (Hi-C)(2), plus chromatin immunoprecipitation (ChIA-PET)(3), have revealed to...

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Udgivet i:Nature
Main Authors: Zheng, Meizhen, Tian, Simon Zhongyuan, Capurso, Daniel, Kim, Minji, Maurya, Rahul, Lee, Byoungkoo, Piecuch, Emaly, Gong, Liang, Zhu, Jacqueline Jufen, Li, Zhihui, Wong, Chee Hong, Ngan, Chew Yee, Wang, Ping, Ruan, Xiaoan, Wei, Chia-Lin, Ruan, Yijun
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001875/
https://ncbi.nlm.nih.gov/pubmed/30778195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-0949-1
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