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Evolutionary analysis of the most polymorphic gene family in falciparum malaria

The var gene family of the human malaria parasite Plasmodium falciparum encode proteins that are crucial determinants of both pathogenesis and immune evasion and are highly polymorphic. Here we have assembled nearly complete var gene repertoires from 2398 field isolates and analysed a normalised set...

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Detalles Bibliográficos
Publicado en:Wellcome Open Res
Autores principales: Otto, Thomas D., Assefa, Sammy A., Böhme, Ulrike, Sanders, Mandy J., Kwiatkowski, Dominic, Berriman, Matt, Newbold, Chris
Formato: Artigo
Lenguaje:Inglês
Publicado: F1000 Research Limited 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001760/
https://ncbi.nlm.nih.gov/pubmed/32055709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.15590.1
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