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Evolutionary analysis of the most polymorphic gene family in falciparum malaria

The var gene family of the human malaria parasite Plasmodium falciparum encode proteins that are crucial determinants of both pathogenesis and immune evasion and are highly polymorphic. Here we have assembled nearly complete var gene repertoires from 2398 field isolates and analysed a normalised set...

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Dades bibliogràfiques
Publicat a:Wellcome Open Res
Autors principals: Otto, Thomas D., Assefa, Sammy A., Böhme, Ulrike, Sanders, Mandy J., Kwiatkowski, Dominic, Berriman, Matt, Newbold, Chris
Format: Artigo
Idioma:Inglês
Publicat: F1000 Research Limited 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001760/
https://ncbi.nlm.nih.gov/pubmed/32055709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.15590.1
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