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Evolutionary analysis of the most polymorphic gene family in falciparum malaria

The var gene family of the human malaria parasite Plasmodium falciparum encode proteins that are crucial determinants of both pathogenesis and immune evasion and are highly polymorphic. Here we have assembled nearly complete var gene repertoires from 2398 field isolates and analysed a normalised set...

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Detalhes bibliográficos
Publicado no:Wellcome Open Res
Main Authors: Otto, Thomas D., Assefa, Sammy A., Böhme, Ulrike, Sanders, Mandy J., Kwiatkowski, Dominic, Berriman, Matt, Newbold, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001760/
https://ncbi.nlm.nih.gov/pubmed/32055709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.15590.1
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