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Mechanistic insights into the inhibition of NTCP by myrcludex B

BACKGROUND & AIMS: The sodium taurocholate co-transporting polypeptide (NTCP) is the entry receptor for the hepatitis B and delta virus (HBV/HDV) and the main hepatic uptake transporter of conjugated bile acids. Myrcludex B, a synthetic peptide mimicking the NTCP-binding domain of HBV, blocks HB...

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Dades bibliogràfiques
Publicat a:JHEP Rep
Autors principals: Donkers, Joanne M., Appelman, Monique D., van de Graaf, Stan F.J.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001544/
https://ncbi.nlm.nih.gov/pubmed/32039379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2019.07.006
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