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Inhibitory Region of Troponin I: Ca(2+)-Dependent Structural and Environmental Changes in the Troponin–Tropomyosin Complex and in Reconstituted Thin Filaments

In muscle thin filaments, the inhibitory region (residues 96–117) of troponin I (TnI) is thought to interact with troponin C (TnC) in the presence of Ca(2+) and with actin in the absence of Ca(2+). To better understand these interactions, we prepared mutant TnIs which contained a single Cys-96 or Cy...

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Dettagli Bibliografici
Pubblicato in:Biochemistry
Autori principali: Kobayashi, Tomoyoshi, Kobayashi, Minae, Gryczynski, Zygmunt, Lakowicz, Joseph R., Collins, John H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001381/
https://ncbi.nlm.nih.gov/pubmed/10625482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi991903b
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