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Ala Scanning of the Inhibitory Region of Cardiac Troponin I
In skeletal and cardiac muscles, troponin (Tn), which resides on the thin filament, senses a change in intracellular Ca(2+) concentration. Tn is composed of TnC, TnI, and TnT. Ca(2+) binding to the regulatory domain of TnC removes the inhibitory effect by TnI on the contraction. The inhibitory regio...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740431/ https://ncbi.nlm.nih.gov/pubmed/19483081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.001396 |
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