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Ala Scanning of the Inhibitory Region of Cardiac Troponin I

In skeletal and cardiac muscles, troponin (Tn), which resides on the thin filament, senses a change in intracellular Ca(2+) concentration. Tn is composed of TnC, TnI, and TnT. Ca(2+) binding to the regulatory domain of TnC removes the inhibitory effect by TnI on the contraction. The inhibitory regio...

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Autori principali: Kobayashi, Tomoyoshi, Patrick, Stacey E., Kobayashi, Minae
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740431/
https://ncbi.nlm.nih.gov/pubmed/19483081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.001396
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