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CLEC14A deficiency exacerbates neuronal loss by increasing blood-brain barrier permeability and inflammation

BACKGROUND: Ischemic stroke is a main cause of mortality. Blood-brain barrier (BBB) breakdown appears to play a critical role in inflammation in patients with ischemic stroke and acceleration of brain injury. The BBB has a protective function and is composed of endothelial cells, pericytes, and astr...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Kim, Yeomyeong, Lee, Sungwoon, Zhang, Haiying, Lee, Sunghye, Kim, Hyejeong, Kim, Yeaji, Won, Moo-Ho, Kim, Young-Myeong, Kwon, Young-Guen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001304/
https://ncbi.nlm.nih.gov/pubmed/32019570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-1727-6
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