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Is tau in the absence of amyloid on the Alzheimer’s continuum?: A study of discordant PET positivity

The amyloid cascade model of Alzheimer’s disease posits the primacy of amyloid beta deposition preceding tau-mediated neurofibrillary tangle formation. The amyloid-tau-neurodegeneration biomarker-only diagnostic framework similarly requires the presence of amyloid beta for a diagnosis on the Alzheim...

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Detalhes bibliográficos
Publicado no:Brain Commun
Main Authors: Weigand, Alexandra J, Bangen, Katherine J, Thomas, Kelsey R, Delano-Wood, Lisa, Gilbert, Paul E, Brickman, Adam M, Bondi, Mark W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001143/
https://ncbi.nlm.nih.gov/pubmed/32051933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcz046
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