Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2

Polycystin-2 (PC2) is a transient receptor potential (TRP) channel present in ciliary membranes of the kidney. PC2 shares a transmembrane fold with other TRP channels, in addition to an extracellular domain found in TRPP and TRPML channels. Using molecular dynamics (MD) simulations and cryoelectron...

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Udgivet i:Structure
Main Authors: Wang, Qinrui, Corey, Robin A., Hedger, George, Aryal, Prafulla, Grieben, Mariana, Nasrallah, Chady, Baronina, Agnese, Pike, Ashley C.W., Shi, Jiye, Carpenter, Elisabeth P., Sansom, Mark S.P.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001106/
https://ncbi.nlm.nih.gov/pubmed/31806353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.11.005
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