Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program

Differentiating neutrophils undergo large-scale changes in nuclear morphology. How such alterations in structure are established and modulated upon exposure to microbial agents is largely unknown. Here, we found that prior to encounter with bacteria, an armamentarium of inflammatory genes was positi...

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Detaylı Bibliyografya
Yayımlandı:Genes Dev
Asıl Yazarlar: Denholtz, Matthew, Zhu, Yina, He, Zhaoren, Lu, Hanbin, Isoda, Takeshi, Döhrmann, Simon, Nizet, Victor, Murre, Cornelis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2020
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000913/
https://ncbi.nlm.nih.gov/pubmed/31919189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.333708.119
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