Left atrial dysfunction in sickle cell anemia is associated with diffuse myocardial fibrosis, increased right ventricular pressure and reduced exercise capacity

Increased extracellular volume (ECV) by CMR is a marker of interstitial myocardial fibrosis and is associated with diastolic dysfunction in sickle cell anemia (SCA). Left atrial (LA) dysfunction and stiffness contribute to the development of diastolic heart failure in other settings. We aimed to eva...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Alsaied, Tarek, Niss, Omar, Tretter, Justin T., Powell, Adam W., Chin, Clifford, Fleck, Robert J., Cnota, James F., Malik, Punam, Quinn, Charles T., Nagueh, Sherif M., Taylor, Michael D., Mazur, Wojciech M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000788/
https://ncbi.nlm.nih.gov/pubmed/32019991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58662-8
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