Association between diffuse myocardial fibrosis and diastolic dysfunction in sickle cell anemia

Sickle cell anemia (SCA)–related cardiomyopathy is characterized by diastolic dysfunction and hyperdynamic features. Diastolic dysfunction portends early mortality in SCA. Diastolic dysfunction is associated with microscopic myocardial fibrosis in SCA mice, but the cause of diastolic dysfunction in...

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Niss, Omar, Fleck, Robert, Makue, Fowe, Alsaied, Tarek, Desai, Payal, Towbin, Jeffrey A., Malik, Punam, Taylor, Michael D., Quinn, Charles T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2017
Schlagworte:
Red Cells, Iron, and Erythropoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510791/
https://ncbi.nlm.nih.gov/pubmed/28507082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-02-767624
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