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A CRISPR/Cas13-based approach demonstrates biological relevance of vlinc class of long non-coding RNAs in anticancer drug response

Long non-coding (lnc) RNAs represent a fascinating class of transcripts that remains highly controversial mainly due to ambiguity surrounding overall biological relevance of these RNAs. Multitude of reverse genetics studies showing functionality of lncRNAs are unfortunately based on assays that are...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Xu, Dongyang, Cai, Ye, Tang, Lu, Han, Xueer, Gao, Fan, Cao, Huifen, Qi, Fei, Kapranov, Philipp
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000768/
https://ncbi.nlm.nih.gov/pubmed/32020014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58104-5
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