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A CRISPR/Cas13-based approach demonstrates biological relevance of vlinc class of long non-coding RNAs in anticancer drug response

Long non-coding (lnc) RNAs represent a fascinating class of transcripts that remains highly controversial mainly due to ambiguity surrounding overall biological relevance of these RNAs. Multitude of reverse genetics studies showing functionality of lncRNAs are unfortunately based on assays that are...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xu, Dongyang, Cai, Ye, Tang, Lu, Han, Xueer, Gao, Fan, Cao, Huifen, Qi, Fei, Kapranov, Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000768/
https://ncbi.nlm.nih.gov/pubmed/32020014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58104-5
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