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Engaging chromatin: PRC2 structure meets function

Polycomb repressive complex 2 (PRC2) is a key epigenetic multiprotein complex involved in the regulation of gene expression in metazoans. PRC2 is formed by a tetrameric core that endows the complex with histone methyltransferase activity, allowing it to mono-, di- and tri-methylate histone H3 on lys...

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Dades bibliogràfiques
Publicat a:Br J Cancer
Autors principals: Chammas, Paul, Mocavini, Ivano, Di Croce, Luciano
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000746/
https://ncbi.nlm.nih.gov/pubmed/31708574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0615-2
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