Oncogene-dependent function of BRG1 in hepatocarcinogenesis

Hepatocellular carcinoma (HCC) is the major type of primary liver cancer. Genomic studies have revealed that HCC is a heterogeneous disease with multiple subtypes. BRG1, encoded by the SMARCA4 gene, is a key component of SWI/SNF chromatin-remodeling complexes. Based on TCGA studies, somatic mutation...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Pan, Song, Xinhua, Cao, Dan, Cui, Kairong, Wang, Jingxiao, Utpatel, Kirsten, Shang, Runze, Wang, Haichuan, Che, Li, Evert, Matthias, Zhao, Keji, Calvisi, Diego F., Chen, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000409/
https://ncbi.nlm.nih.gov/pubmed/32019910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2289-3
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