Mesenchymal stem cells ameliorate β cell dysfunction of human type 2 diabetic islets by reversing β cell dedifferentiation

BACKGROUND: A physiological hallmark of patients with type 2 diabetes mellitus (T2DM) is β cell dysfunction. Despite adequate treatment, it is an irreversible process that follows disease progression. Therefore, the development of novel therapies that restore β cell function is of utmost importance....

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Vydáno v:EBioMedicine
Hlavní autoři: Wang, Le, Liu, Tengli, Liang, Rui, Wang, Guanqiao, Liu, Yaojuan, Zou, Jiaqi, Liu, Na, Zhang, Boya, Liu, Yan, Ding, Xuejie, Cai, Xiangheng, Wang, Zhiping, Xu, Xiumin, Ricordi, Camillo, Wang, Shusen, Shen, Zhongyang
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
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Research paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000334/
https://ncbi.nlm.nih.gov/pubmed/31918404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.102615
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