Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia

The hippocampus formation, although prominently implicated in schizophrenia pathogenesis, has been overlooked in large-scale genomics efforts in the schizophrenic brain. We performed RNA-seq in hippocampi and dorsolateral prefrontal cortices (DLPFCs) from 551 individuals (286 with schizophrenia). We...

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Publié dans:Neuron
Auteurs principaux: Collado-Torres, Leonardo, Burke, Emily E., Peterson, Amy, Shin, JooHeon, Straub, Richard E., Rajpurohit, Anandita, Semick, Stephen A., Ulrich, William S., Price, Amanda J., Valencia, Cristian, Tao, Ran, Deep-Soboslay, Amy, Hyde, Thomas M., Kleinman, Joel E., Weinberger, Daniel R., Jaffe, Andrew E.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000204/
https://ncbi.nlm.nih.gov/pubmed/31174959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.05.013
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