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Mapping DNA methylation across development, genotype, and schizophrenia in the human frontal cortex

DNA methylation (DNAm) is important in brain development, and potentially in schizophrenia. We characterized DNAm in prefrontal cortex from 335 non-psychiatric controls across the lifespan and 191 patients with schizophrenia, and identified widespread changes in the transition from prenatal to postn...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Jaffe, Andrew E., Gao, Yuan, Deep-Soboslay, Amy, Tao, Ran, Hyde, Thomas M., Weinberger, Daniel R., Kleinman, Joel E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783176/
https://ncbi.nlm.nih.gov/pubmed/26619358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4181
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