Enrichment of miR-126 enhances the effects of endothelial progenitor cell–derived microvesicles on modulating MC3T3-E1 cell function via Erk1/2-Bcl-2 signalling pathway

Objective: To evaluate whether EPC-MVs could promote bone regeneration by directly regulating osteoblast through miR-126. The underlying mechanisms were also explored. Methods: EPCs were isolated from bone marrow mononuclear cells. EPC-MVs were collected from EPCs cultured medium. The lentivirus was...

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Dettagli Bibliografici
Pubblicato in:Prion
Autori principali: Chen, Guanghua, Li, Peng, Liu, Zhijun, Zeng, Rong, Ma, Xiaotang, Chen, Yanfang, Xu, Haijia, Li, Zhanghua, Lin, Hao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2019
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000145/
https://ncbi.nlm.nih.gov/pubmed/31050590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2019.1607464
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