Evidence for Involvement of ERK, PI3K, and RSK in Induction of Bcl-2 by Valproate

Valproate, an anticonvulsant and mood stabilizer, up-regulates Bcl-2, a neurotrophic/neuroprotective protein. In this study, we investigated the molecular mechanism through which Bcl-2 is up-regulated by valproate using cultured human neuron-like cells. Valproate, within therapeutically relevant ran...

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Bibliographic Details
Main Authors:	Creson, Thomas K., Yuan, Peixiong, Manji, Husseini K., Chen, Guang
Format:	Artigo
Language:	Inglês
Published:	2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2788987/ https://ncbi.nlm.nih.gov/pubmed/18677583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-008-9122-2
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Evidence for Involvement of ERK, PI3K, and RSK in Induction of Bcl-2 by Valproate

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