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Evidence for Involvement of ERK, PI3K, and RSK in Induction of Bcl-2 by Valproate

Valproate, an anticonvulsant and mood stabilizer, up-regulates Bcl-2, a neurotrophic/neuroprotective protein. In this study, we investigated the molecular mechanism through which Bcl-2 is up-regulated by valproate using cultured human neuron-like cells. Valproate, within therapeutically relevant ran...

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Autores principales: Creson, Thomas K., Yuan, Peixiong, Manji, Husseini K., Chen, Guang
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788987/
https://ncbi.nlm.nih.gov/pubmed/18677583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-008-9122-2
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