Structural and biophysical properties of RIG-I bound to dsRNA with G-U wobble base pairs

Retinoic acid-inducible gene I (RIG-I) is responsible for innate immunity via the recognition of short double-stranded RNAs in the cytosol. With the clue that G-U wobble base pairs in the influenza A virus’s RNA promoter region are responsible for RIG-I activation, we determined the complex structur...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:RNA Biol
Prif Awduron: Kim, Ki-Hun, Hwang, Jihyun, Kim, Jin Hong, Son, Kyung-Pyo, Jang, Yejin, Kim, Meehyein, Kang, Suk-Jo, Lee, Jie-Oh, Kang, Jin Young, Choi, Byong-Seok
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2019
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999645/
https://ncbi.nlm.nih.gov/pubmed/31852354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1700034
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