Structural and biophysical properties of RIG-I bound to dsRNA with G-U wobble base pairs

Retinoic acid-inducible gene I (RIG-I) is responsible for innate immunity via the recognition of short double-stranded RNAs in the cytosol. With the clue that G-U wobble base pairs in the influenza A virus’s RNA promoter region are responsible for RIG-I activation, we determined the complex structur...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Kim, Ki-Hun, Hwang, Jihyun, Kim, Jin Hong, Son, Kyung-Pyo, Jang, Yejin, Kim, Meehyein, Kang, Suk-Jo, Lee, Jie-Oh, Kang, Jin Young, Choi, Byong-Seok
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999645/
https://ncbi.nlm.nih.gov/pubmed/31852354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1700034
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