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Global proteome response of Escherichia coli BL21 to production of human basic fibroblast growth factor in complex and defined medium

The global proteome response toward recombinant protein production in Escherichia coli BL21 (DE3) grown in complex and defined medium was analyzed. Overproduction of human basic fibroblast growth factor (hFGF‐2), a difficult‐to‐fold protein, led to a reconstruction of the bacterial proteome. For exa...

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Bibliografiske detaljer
Udgivet i:Eng Life Sci
Main Authors: Li, Zhaopeng, Nimtz, Manfred, Rinas, Ursula
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999367/
https://ncbi.nlm.nih.gov/pubmed/32624836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elsc.201700036
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