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Global proteome response of Escherichia coli BL21 to production of human basic fibroblast growth factor in complex and defined medium

The global proteome response toward recombinant protein production in Escherichia coli BL21 (DE3) grown in complex and defined medium was analyzed. Overproduction of human basic fibroblast growth factor (hFGF‐2), a difficult‐to‐fold protein, led to a reconstruction of the bacterial proteome. For exa...

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Detalhes bibliográficos
Publicado no:Eng Life Sci
Main Authors: Li, Zhaopeng, Nimtz, Manfred, Rinas, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999367/
https://ncbi.nlm.nih.gov/pubmed/32624836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elsc.201700036
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