Nasal Pneumococcal Density Is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens

Rationale: Pneumococcal pneumonia remains a global health problem. Colonization of the nasopharynx with Streptococcus pneumoniae (Spn), although a prerequisite of infection, is the main source of exposure and immunological boosting in children and adults. However, our knowledge of how nasal coloniza...

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Bibliografske podrobnosti
izdano v:Am J Respir Crit Care Med
Main Authors: Mitsi, Elena, Carniel, Beatriz, Reiné, Jesús, Rylance, Jamie, Zaidi, Seher, Soares-Schanoski, Alessandra, Connor, Victoria, Collins, Andrea M., Schlitzer, Andreas, Nikolaou, Elissavet, Solórzano, Carla, Pojar, Sherin, Hill, Helen, Hyder-Wright, Angela D., Jambo, Kondwani C., Oggioni, Marco R., De Ste Croix, Megan, Gordon, Stephen B., Jochems, Simon P., Ferreira, Daniela M.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2020
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999099/
https://ncbi.nlm.nih.gov/pubmed/31626559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201903-0607OC
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