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A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic

BACKGROUND: Atypical Beijing genotype Mycobacterium tuberculosis strains are widespread in South Africa and have acquired resistance to up to 13 drugs on multiple occasions. It is puzzling that these strains have retained fitness and transmissibility despite the potential fitness cost associated wit...

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: Klopper, Marisa, Heupink, Tim Hermanus, Hill-Cawthorne, Grant, Streicher, Elizabeth Maria, Dippenaar, Anzaan, de Vos, Margaretha, Abdallah, Abdallah Musa, Limberis, Jason, Merker, Matthias, Burns, Scott, Niemann, Stefan, Dheda, Keertan, Posey, James, Pain, Arnab, Warren, Robin Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6998097/
https://ncbi.nlm.nih.gov/pubmed/32014024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-019-1487-2
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