A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic

BACKGROUND: Atypical Beijing genotype Mycobacterium tuberculosis strains are widespread in South Africa and have acquired resistance to up to 13 drugs on multiple occasions. It is puzzling that these strains have retained fitness and transmissibility despite the potential fitness cost associated wit...

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Detaylı Bibliyografya
Yayımlandı:BMC Med
Asıl Yazarlar: Klopper, Marisa, Heupink, Tim Hermanus, Hill-Cawthorne, Grant, Streicher, Elizabeth Maria, Dippenaar, Anzaan, de Vos, Margaretha, Abdallah, Abdallah Musa, Limberis, Jason, Merker, Matthias, Burns, Scott, Niemann, Stefan, Dheda, Keertan, Posey, James, Pain, Arnab, Warren, Robin Mark
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6998097/
https://ncbi.nlm.nih.gov/pubmed/32014024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-019-1487-2
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