Galectin-3 coordinates a cellular system for lysosomal repair and removal

Endomembrane damage elicits homeostatic responses including ESCRT-dependent membrane repair and autophagic removal of damaged organelles. Previous studies have suggested that these systems may act separately. Here we show that galectin-3 (Gal3), a β-galactoside binding cytosolic lectin, unifies and...

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Vydáno v:Dev Cell
Hlavní autoři: Jia, Jingyue, Claude-Taupin, Aurore, Gu, Yuexi, Choi, Seong Won, Peters, Ryan, Bissa, Bhawana, Mudd, Michal H., Allers, Lee, Pallikkuth, Sandeep, Lidke, Keith A., Salemi, Michelle, Phinney, Brett, Mari, Muriel, Reggiori, Fulvio, Deretic, Vojo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997950/
https://ncbi.nlm.nih.gov/pubmed/31813797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.10.025
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