Sildenafil Prevents Marfan-Associated Emphysema and Early Pulmonary Artery Dilation in Mice

Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in fibrillin-1 (Fbn1). Although aortic rupture is the major cause of mortality in MFS, patients also experience pulmonary complications, which are poorly understood. Loss of basal nitric oxide (NO) production and vascular inte...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Am J Pathol
Autori principali: White, Zoe, Milad, Nadia, Tehrani, Arash Y., Lamothe, Jennifer, Hogg, James C., Esfandiarei, Mitra, Seidman, Michael, Booth, Steven, Hackett, Tillie-Louise, Morissette, Mathieu C., Bernatchez, Pascal
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997843/
https://ncbi.nlm.nih.gov/pubmed/31125551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.05.003
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi