Mutations in EZH2 are associated with poor prognosis for patients with myeloid neoplasms

EZH2 is a component of the polycomb repressive complex 2 (PRC2), which is a highly conserved histone methyltransferase that methylates lysine 27 of histone 3. EZH2 mutations are associated with oncogenesis and progression of cancers. However, the relationship between the clinical outcome of patients...

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Bibliographische Detailangaben
Veröffentlicht in:Genes Dis
Hauptverfasser: Zhang, Qi, Han, Qi, Zi, Jie, Ma, Jinlong, Song, Huihui, Tian, Yulu, McGrath, Mary, Song, Chunhua, Ge, Zheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Chongqing Medical University 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997607/
https://ncbi.nlm.nih.gov/pubmed/32042866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2019.05.001
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