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A nematode sterol C4α-methyltransferase catalyzes a new methylation reaction responsible for sterol diversity

Primitive sterol evolution plays an important role in fossil record interpretation and offers potential therapeutic avenues for human disease resulting from nematode infections. Recognizing that C4-methyl stenol products [8(14)-lophenol] can be synthesized in bacteria while C4-methyl stanol products...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Zhou, Wenxu, Fisher, Paxtyn M., Vanderloop, Boden H., Shen, Yun, Shi, Huazhong, Maldonado, Adrian J., Leaver, David J., Nes, W. David
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997595/
https://ncbi.nlm.nih.gov/pubmed/31548366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000317
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