Aspergillus fumigatus Infection in Humans With STAT3-Deficiency Is Associated With Defective Interferon-Gamma and Th17 Responses

In humans, loss-of-function mutation in the Signal Transducer and Activator of Transcription 3 (STAT3) gene is frequently associated with susceptibility to bacterial as well as fungal infections including aspergillosis, although its pathogenesis remains largely unknown. In the present study, we inve...

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Pubblicato in:Front Immunol
Autori principali: Danion, François, Aimanianda, Vishukumar, Bayry, Jagadeesh, Duréault, Amélie, Wong, Sarah Sze Wah, Bougnoux, Marie-Elisabeth, Tcherakian, Colas, Alyanakian, Marie-Alexandra, Guegan, Hélène, Puel, Anne, Picard, Capucine, Lortholary, Olivier, Lanternier, Fanny, Latgé, Jean-Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997434/
https://ncbi.nlm.nih.gov/pubmed/32047500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00038
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