Fungal melanin stimulates surfactant protein D–mediated opsonization of and host immune response to Aspergillus fumigatus spores

Surfactant protein D (SP-D), a C-type lectin and pattern-recognition soluble factor, plays an important role in immune surveillance to detect and eliminate human pulmonary pathogens. SP-D has been shown to protect against infections with the most ubiquitous airborne fungal pathogen, Aspergillus fumi...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Wong, Sarah Sze Wah, Rani, Manjusha, Dodagatta-Marri, Eswari, Ibrahim-Granet, Oumaima, Kishore, Uday, Bayry, Jagadeesh, Latgé, Jean-Paul, Sahu, Arvind, Madan, Taruna, Aimanianda, Vishukumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880149/
https://ncbi.nlm.nih.gov/pubmed/29414772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.815852
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