Aspergillus fumigatus conidial metalloprotease Mep1p cleaves host complement proteins

Innate immunity in animals including humans encompasses the complement system, which is considered an important host defense mechanism against Aspergillus fumigatus, one of the most ubiquitous opportunistic human fungal pathogens. Previously, it has been shown that the alkaline protease Alp1p secret...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Shende, Rajashri, Wong, Sarah Sze Wah, Rapole, Srikanth, Beau, Rémi, Ibrahim-Granet, Oumaima, Monod, Michel, Gührs, Karl-Heinz, Pal, Jayanta Kumar, Latgé, Jean-Paul, Madan, Taruna, Aimanianda, Vishukumar, Sahu, Arvind
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2018
Aiheet:
Immunology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177592/
https://ncbi.nlm.nih.gov/pubmed/30139746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001476
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