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A genome‐wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells

To ensure proper transmission of genetic information, cells need to preserve and faithfully replicate their genome, and failure to do so leads to genome instability, a hallmark of both cancer and aging. Defects in genes involved in guarding genome stability cause several human progeroid syndromes, a...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Novarina, Daniele, Janssens, Georges E., Bokern, Koen, Schut, Tim, van Oerle, Noor C., Kazemier, Hinke G., Veenhoff, Liesbeth M., Chang, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996960/
https://ncbi.nlm.nih.gov/pubmed/31854076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13084
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