A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models

Accumulating studies have suggested that targeting transcription factor EB (TFEB), an essential regulator of autophagy‐lysosomal pathway (ALP), is promising for the treatment of neurodegenerative disorders, including Alzheimer's disease (AD). However, potent and specific small molecule TFEB act...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Aging Cell
Päätekijät: Song, Ju‐Xian, Malampati, Sandeep, Zeng, Yu, Durairajan, Siva Sundara Kumar, Yang, Chuan‐Bin, Tong, Benjamin Chun‐Kit, Iyaswamy, Ashok, Shang, Wen‐Bin, Sreenivasmurthy, Sravan Gopalkrishnashetty, Zhu, Zhou, Cheung, King‐Ho, Lu, Jia‐Hong, Tang, Chunzhi, Xu, Nenggui, Li, Min
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996953/
https://ncbi.nlm.nih.gov/pubmed/31858697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13069
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