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A modified formulation of Huanglian-Jie-Du-Tang reduces memory impairments and β-amyloid plaques in a triple transgenic mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is a degenerative disorder typified by progressive deterioration of memory and the appearance of β-amyloid peptide (Aβ)-rich senile plaques. Recently we have identified a novel function of a patented formulation of modified Huanglian-Jie-Tu-Tang (HLJDT-M), a Chinese herbal m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Durairajan, Siva Sundara Kumar, Iyaswamy, Ashok, Shetty, Sravan Gopalakrishna, Kammella, Ananth Kumar, Malampati, Sandeep, Shang, Wenbin, Yang, Chuanbin, Song, Juxian, Chung, Sookja, Huang, Jiandong, Ilango, Kaliappan, Han, Quan-Bin, Li, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524904/
https://ncbi.nlm.nih.gov/pubmed/28740171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06217-9
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