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CHIP modulates APP‐induced autophagy‐dependent pathological symptoms in Drosophila

Dysregulation of autophagy is associated with the neurodegenerative processes in Alzheimer's disease (AD), yet it remains controversial whether autophagy is a cause or consequence of AD. We have previously expressed the full‐length human APP in Drosophila and established a fly AD model that exh...

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Zhuang, Luming, Peng, Fei, Huang, Yuanyuan, Li, Wenzhe, Huang, Jiuhong, Chu, Yunqiang, Ren, Pu, Sun, Ying, Zhang, Yan, Xue, Elleen, Guo, Xiaowei, Shen, Xiafeng, Xue, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996943/
https://ncbi.nlm.nih.gov/pubmed/31777182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13070
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