FOXL2 homozygous genotype and chromosome instability are associated with recurrence in adult granulosa cell tumors of the ovary

Introduction: Adult granulosa cell tumors (aGCTs) are extremely rare tumors characterized by the presence of the single missense mutation (c.402 C>G, p. C134W) in the FOXL2 gene. These tumors are frequently associated with a slow, indolent disease progression and a high probability of aggressive...

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Udgivet i:Oncotarget
Main Authors: Kraus, Francois, Dremaux, Julie, Altakfi, Wajd, Goux, Magalie, Pontois, Léa, Sevestre, Henri, Trudel, Stéphanie
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996913/
https://ncbi.nlm.nih.gov/pubmed/32064045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27447
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