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Finding the gas pedal on a slow sirtuin

The class III histone deacetylase sirtuin 6 (SIRT6) modulates numerous functions in the cell by deacetylating histone lysine residues. Interestingly, SIRT6's efficiency in in vitro experiments is far greater against substrates carrying long-chain fatty acyl modifications such as myristoylated l...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Nielsen, Alexander L., Olsen, Christian A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996887/
https://ncbi.nlm.nih.gov/pubmed/32005646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H120.012534
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