ACE overexpression in myeloid cells increases oxidative metabolism and cellular ATP

Angiotensin-converting enzyme (ACE) affects blood pressure. In addition, ACE overexpression in myeloid cells increases their immune function. Using MS and chemical analysis, we identified marked changes of intermediate metabolites in ACE-overexpressing macrophages and neutrophils, with increased cel...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cao, Duo-Yao, Spivia, Weston R., Veiras, Luciana C., Khan, Zakir, Peng, Zhenzi, Jones, Anthony E., Bernstein, Ellen A., Saito, Suguru, Okwan-Duodu, Derick, Parker, Sarah J., Giani, Jorge F., Divakaruni, Ajit S., Van Eyk, Jennifer E., Bernstein, Kenneth E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996878/
https://ncbi.nlm.nih.gov/pubmed/31871049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011244
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