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ACE overexpression in myeloid cells increases oxidative metabolism and cellular ATP

Angiotensin-converting enzyme (ACE) affects blood pressure. In addition, ACE overexpression in myeloid cells increases their immune function. Using MS and chemical analysis, we identified marked changes of intermediate metabolites in ACE-overexpressing macrophages and neutrophils, with increased cel...

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Podrobná bibliografie
Vydáno v:J Biol Chem
Hlavní autoři: Cao, Duo-Yao, Spivia, Weston R., Veiras, Luciana C., Khan, Zakir, Peng, Zhenzi, Jones, Anthony E., Bernstein, Ellen A., Saito, Suguru, Okwan-Duodu, Derick, Parker, Sarah J., Giani, Jorge F., Divakaruni, Ajit S., Van Eyk, Jennifer E., Bernstein, Kenneth E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996878/
https://ncbi.nlm.nih.gov/pubmed/31871049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011244
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