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Dexamethasone promotes mesenchymal stem cell apoptosis and inhibits osteogenesis by disrupting mitochondrial dynamics

Long‐term or heavy use of glucocorticoids can cause severe necrosis of the femoral head, but the underlying mechanisms are still unclear. Recent studies have found that mitochondrial dynamics play an important role in femoral head necrosis. Here, we investigated the effect of dexamethasone on the mi...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Ma, Liang, Feng, Xiaobo, Wang, Kun, Song, Yu, Luo, Rongjin, Yang, Cao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996403/
https://ncbi.nlm.nih.gov/pubmed/31788976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12771
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