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Changes in the R‐region interactions depend on phosphorylation and contribute to PKA and PKC regulation of the cystic fibrosis transmembrane conductance regulator chloride channel
The CFTR chloride channel is regulated by phosphorylation at PKA and PKC consensus sites within its regulatory region (R‐region) through a mechanism, which is still not completely understood. We used a split‐CFTR construct expressing the N‐term‐TMD1‐NBD1 (Front Half; FH), TMD2‐NBD2‐C‐Term (Back Half...
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| Gepubliceerd in: | FASEB Bioadv |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6996395/ https://ncbi.nlm.nih.gov/pubmed/32123855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2019-00053 |
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