Glutathione increase by the n‐butanoyl glutathione derivative (GSH‐C4) inhibits viral replication and induces a predominant Th1 immune profile in old mice infected with influenza virus

During aging, glutathione (GSH) content declines and the immune system undergoes a deficiency in the induction of Th1 response. Reduced secretion of Th1 cytokines, which is associated with GSH depletion, could weaken the host defenses against viral infections. We first evaluated the concentration of...

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Detalhes bibliográficos
Publicado no:FASEB Bioadv
Main Authors: Amatore, Donatella, Celestino, Ignacio, Brundu, Serena, Galluzzi, Luca, Coluccio, Paolo, Checconi, Paola, Magnani, Mauro, Palamara, Anna Teresa, Fraternale, Alessandra, Nencioni, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996388/
https://ncbi.nlm.nih.gov/pubmed/32123833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2018-00066
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