GSH-C4 Acts as Anti-inflammatory Drug in Different Models of Canonical and Cell Autonomous Inflammation Through NFκB Inhibition

An imbalance in GSH/GSSG ratio represents a triggering event in pro-inflammatory cytokine production and inflammatory response. However, the molecular mechanism(s) through which GSH regulates macrophage and cell autonomous inflammation remains not deeply understood. Here, we investigated the effects...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Limongi, Dolores, Baldelli, Sara, Checconi, Paola, Marcocci, Maria Elena, De Chiara, Giovanna, Fraternale, Alessandra, Magnani, Mauro, Ciriolo, Maria Rosa, Palamara, Anna Teresa
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2019
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6372722/
https://ncbi.nlm.nih.gov/pubmed/30787932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00155
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