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Losing maleness: Somatic Y chromosome loss at every stage of a man's life

Mosaic loss of Y chromosome (LOY) is assumed to be among the most common acquired genetic variations in elderly people. Recent studies have linked aging‐related mosaic LOY to the risk of Alzheimer's disease, cancer, and early death. Here, we propose that mosaic LOY can present in men at any age...

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Bibliografiske detaljer
Udgivet i:FASEB Bioadv
Main Authors: Miyado, Mami, Fukami, Maki
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996334/
https://ncbi.nlm.nih.gov/pubmed/32123838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2019-00006
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