Copy‐number analysis of Y‐linked loci in young men with non‐obstructive azoospermia: Implications for the rarity of early onset mosaic loss of chromosome Y

PURPOSE: Mosaic loss of chromosome Y (mLOY) is a common feature in elderly men. If mLOY can also occur in young men, it may lead to spermatogenic failure due to loss of spermatogenic genes. Indeed, previous studies detected the 45,X/46,XY karyotype in a few young men with spermatogenic failure. The...

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Detalhes bibliográficos
Publicado no:Reprod Med Biol
Main Authors: Suzuki, Erina, Kobori, Yoshitomo, Katsumi, Momori, Ushijima, Kikumi, Uchiyama, Toru, Okada, Hiroshi, Miyado, Mami, Fukami, Maki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138941/
https://ncbi.nlm.nih.gov/pubmed/32273824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rmb2.12321
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