Manipulation of the tumor microenvironment by cytokine gene transfection enhances dendritic cell‐based immunotherapy

The tumor microenvironment strongly influences clinical outcomes of immunotherapy. By transfecting genes of relevant cytokines into tumor cells, we sought to manipulate the microenvironment so as to elicit activation of T helper type 1 (Th1) responses and the maturation of dendritic cells (DCs). Usi...

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發表在:FASEB Bioadv
Main Authors: Wijesekera, Daluthgamage Patsy Himali, Yuba, Eiji, De Silva, Nadeeka Harshini, Watanabe, Shun‐ichi, Tsukamoto, Masaya, Ichida, Chihiro, Izawa, Takeshi, Itoh, Kazuyuki, Kanegi, Ryoji, Hatoya, Shingo, Yamate, Jyoji, Inaba, Toshio, Sugiura, Kikuya
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996313/
https://ncbi.nlm.nih.gov/pubmed/32123853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2019-00052
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