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Manipulation of the tumor microenvironment by cytokine gene transfection enhances dendritic cell‐based immunotherapy

The tumor microenvironment strongly influences clinical outcomes of immunotherapy. By transfecting genes of relevant cytokines into tumor cells, we sought to manipulate the microenvironment so as to elicit activation of T helper type 1 (Th1) responses and the maturation of dendritic cells (DCs). Usi...

詳細記述

保存先:
書誌詳細
出版年:FASEB Bioadv
主要な著者: Wijesekera, Daluthgamage Patsy Himali, Yuba, Eiji, De Silva, Nadeeka Harshini, Watanabe, Shun‐ichi, Tsukamoto, Masaya, Ichida, Chihiro, Izawa, Takeshi, Itoh, Kazuyuki, Kanegi, Ryoji, Hatoya, Shingo, Yamate, Jyoji, Inaba, Toshio, Sugiura, Kikuya
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996313/
https://ncbi.nlm.nih.gov/pubmed/32123853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2019-00052
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